Urotsukidōji: Legend of the Overfiend (1989)

Legend has it that the human race is not the only dominant civilization living on Earth. Two other races exist in this world: the Makai (a demon race) and the Jujinkai (a half-man, half-beast race). Once every 3,000 years, a supreme being known as the “Choujin” (Overfiend) will emerge and bring balance to all three realms on Earth. In present-day Japan, after 300 years of endless searching, a Jujinkai named Amano Jyaku has discovered the presence of the Choujin inside high school slacker Tatsuo Nagumo. But now, Amano, along with his sister Megumi and their sidekick Kuroko must protect Nagumo and his new girlfriend Akemi Ito from the Makai, who believe that Nagumo is not the Choujin, but an evil entity bent on destroying all living beings on Earth.
Hideki Takayama
Tomohiro Nishimura, Tsutomu Kashiwakura, Kenyu Horiuchi, Maya Okamoto, Hirotaka Suzuoki, Nobuo Tobita, Yoko Asagami, Koichi Yamadera, Kyounosuke Hiruma, Norio Wakamoto, Daisuke Gori, Hidetoshi Nakamura, Kenichi Ono, Koji Totani, Minako Arakawa, Miyuki Matsushita, Mizuka Arima, Narumi Tsunoda, Natsumi Sasaki, Nobuo Tobita, Satoko Kitô, Shigeru Nakahara, Shinji Ogawa, Yumi Takada
tt0108461